I recently got a new laptop for work, and had to install a bunch of stuff. For what it’s worth here’s what made it in within the first couple of days:

• 1Password
• DropBox (these two together are literally the first thing I install)
• Evernote
• Quick Search Box (QuickSilver replacement; either is fine for what I do)
• Skype (Needed for work, for personal IM I use Adium with the Skype plugin)
• TextMate (with AckMate)
• TinyAlarm
• Xmarks
• XSlimmer (because of my OCD)